His research is in the fields of complex analysis in several variables, harmonic analysis, and operator theory. He is particularly interested in the Bergman kernel, the Bergman projection, and mapping properties of operators in several complex variables. His teaching interests at Duke Kunshan University include MATH 105 Calculus, MATH 307 Complex Analysis, and MATH 308 Real Analysis.

Huo has a B.Sc. in mathematics from Wuhan University, and a Ph.D. in mathematics from the University of Illinois, Urbana-Champaign. From 2016 to 2018, he worked at Washington University in St. Louis as a postdoctoral fellow. Before joining Duke Kunshan, he was a visiting faculty at the University of Toledo.