Tommaso's academic interests center on the transmission of knowledge and culture across diverse communities and languages in Antiquity and Late Antiquity, with a primary focus on the Near Eastern and Eastern Mediterranean regions. His first book, published by Oxford University Press in 2024, explores apocalypticism and ideology in Roman and Iranian societies during the reign of Justinian (6th century CE). He is currently working on a second book examining the reception of the Babylonian Gilgamesh Epic in late antique legends surrounding Alexander the Great and in the Qur'an.

Tommaso earned his Ph.D. through a joint program between the Department of Oriental Studies at the University of Rome (La Sapienza) and the Department of Arabic Studies at the Institut National des Langues et Civilisations Orientales (INALCO) in Paris. From 2018 to 2019, he was the Patricia Crone Member at the Institute for Advanced Study in Princeton. Before that, he spent five years as a Polonsky Research Fellow at the Van Leer Jerusalem Institute in Jerusalem.